Ozempic vs Wegovy: Same medication, different purpose.

Quick answer

Ozempic and Wegovy both contain semaglutide, but they’re approved and used differently. In general, Ozempic is used for type 2 diabetes management, while Wegovy is approved for chronic weight management in eligible adults. Wegovy also has an indication related to reducing certain cardiovascular risks in specific adults with overweight/obesity and established cardiovascular disease.

If you’re deciding between them, the “right” option depends on your health goals, medical history, and what a provider determines is appropriate.

Ozempic vs Wegovy: side-by-side

What they have in common

• Same active ingredient: semaglutide
• Same medication class: GLP-1 receptor agonist
• Similar common side effects (GI-related like nausea, vomiting, diarrhea, constipation, abdominal pain)
• Work best with nutrition, activity, and behavior support

Key differences

• Primary approved use: diabetes care (Ozempic) vs weight management (Wegovy)
• Typical dosing targets: Wegovy is generally titrated to a higher maintenance dose than Ozempic (your provider decides what’s appropriate)
• Insurance/cost dynamics: coverage often differs depending on whether the plan covers diabetes meds vs weight-loss meds

Which one is “better” for weight loss?

For many people seeking weight management support, Wegovy is the branded semaglutide option specifically approved for that purpose. Ozempic is commonly discussed online for weight loss, but its core approval is for type 2 diabetes care. A provider can help clarify options based on your goals and eligibility.

Best next step: take the quiz to see whether you should start with labs, a provider consult, or a program pathway.

Side effects: what to expect (and how people manage them)

The most common side effects with semaglutide are gastrointestinal.
Many people reduce discomfort by:

• Eating smaller meals and slowing down while eating
• Prioritizing hydration and fiber (as tolerated)
• Avoiding very greasy foods during dose increases
• Following a gradual titration plan per provider guidance

If symptoms are severe or persistent, you should reach out to a clinician promptly.

Safety notes (important)

GLP-1 medications aren’t right for everyone. Eligibility depends on your medical history and risk factors, and a provider should review any contraindications or warning signs. If you have severe symptoms, signs of dehydration, or anything urgent, seek immediate medical care.

Ready to choose your next step?

Most people do best starting with one of these:

1. Take the GLP-1 Quiz (fastest way to get matched)
2. Order labs first (if you want data-driven guidance)
3. Book a consult (if you want to talk it through)